Comparison of Ventilation and Voice Outcomes between Unilateral Laryngeal Pacing and Unilateral Cordotomy for the Treatment of Bilateral Vocal Fold Paralysis
Background/Aims: Rehabilitation of the bilaterally paralyzed human larynx remains a complex clinical problem. Conventional treatment generally involves surgical enlargement of the compromised airway, but often with resultant dysphonia and risk of aspiration. In this retrospective study, we compared...
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| Veröffentlicht in: | O.R.L. Journal for oto-rhino-laryngology and its related specialties 2013-01, Vol.75 (2), p.68-73 |
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| container_title | O.R.L. Journal for oto-rhino-laryngology and its related specialties |
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| creator | Li, Yike Pearce, Elizabeth C. Mainthia, Rajshri Athavale, Sanjay M. Dang, Jennifer Ashmead, Daniel H. Garrett, C. Gaelyn Rousseau, Bernard Billante, Cheryl R. Zealear, David L. |
| description | Background/Aims: Rehabilitation of the bilaterally paralyzed human larynx remains a complex clinical problem. Conventional treatment generally involves surgical enlargement of the compromised airway, but often with resultant dysphonia and risk of aspiration. In this retrospective study, we compared one such treatment, posterior cordotomy, with unilateral laryngeal pacing: reanimation of vocal fold opening by functional electrical stimulation of the posterior cricoarytenoid muscle. Methods: Postoperative peak inspiratory flow (PIF) values and overall voice grade ratings were compared between the two surgical groups, and pre- and postoperative PIF were compared within the pacing group. Results: There were 5 patients in the unilateral pacing group and 12 patients in the unilateral cordotomy group. Within the pacing group, postoperative PIF values were significantly improved from preoperative PIF values (p = 0.04) without a significant effect on voice (grade; p = 0.62). Within the pacing group, the mean postoperative PIF value was significantly higher than that in the cordotomy group (p = 0.05). Also, the mean postoperative overall voice grade values in the pacing group were significantly lower (better) than those of the cordotomy group (p = 0.03). Conclusion: Unilateral pacing appears to be an effective treatment superior to posterior cordotomy with respect to postoperative ventilation and voice outcome measures. |
| doi_str_mv | 10.1159/000345501 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1159_000345501</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3040475811</sourcerecordid><originalsourceid>FETCH-LOGICAL-c518t-9366e3e9a4ffe9ff3631ed90b268134c80cde2107416c8f6f3ae3b130e7701273</originalsourceid><addsrcrecordid>eNptkU1vEzEQhi0EomnhwB0hS72Uw4I_9ssXJIgoIEUKQm2uluMdpy67drA3oPwY_isTUlYFcbE9nmfeeUdDyDPOXnFeqdeMMVlWFeMPyIyXQhZMNNVDMmOS8YJXtTohpznfIlaJtnlMToRsZC1LNSM_53HYmuRzDDQ6uoIw-t6MHkMTOrqK3gJd7kYbB8h0DeMPgECvwwGCZHq6MGkfNoCvz8b6sPlddi8_j6mLYxz21MVExxugVwnMOGCjQ8N3E7iKFs_L2HeohB_77PMT8siZPsPTu_uMXF--v5p_LBbLD5_mbxeFrXg7FkrWNUhQpnQOlHM4G4dOsbWoWy5L2zLbgeCsKXltW1c7aUCuuWTQNIyLRp6RN0fd7W49QGfRHDrQ2-QHHE9H4_XfmeBv9CZ-17JRLatrFLi4E0jx2w7yqAefLfS9CRB3WfOScaZEyxSi5_-gt3GXAo6HFG8bgSYFUi-PlE0x5wRuMsOZPixdT0tH9sV99xP5Z8sIPD8CX03aQJqAqf78v-nll8WR0NvOyV9-nL5r</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1418724162</pqid></control><display><type>article</type><title>Comparison of Ventilation and Voice Outcomes between Unilateral Laryngeal Pacing and Unilateral Cordotomy for the Treatment of Bilateral Vocal Fold Paralysis</title><source>Karger Journals</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><source>Karger:Jisc Collections:ORL, Ophthalmology, Dental Medicine, Obstetrics, Gynecology and Psychology, Psychiatry Archive Collection (2012-2112)</source><creator>Li, Yike ; Pearce, Elizabeth C. ; Mainthia, Rajshri ; Athavale, Sanjay M. ; Dang, Jennifer ; Ashmead, Daniel H. ; Garrett, C. Gaelyn ; Rousseau, Bernard ; Billante, Cheryl R. ; Zealear, David L.</creator><creatorcontrib>Li, Yike ; Pearce, Elizabeth C. ; Mainthia, Rajshri ; Athavale, Sanjay M. ; Dang, Jennifer ; Ashmead, Daniel H. ; Garrett, C. Gaelyn ; Rousseau, Bernard ; Billante, Cheryl R. ; Zealear, David L.</creatorcontrib><description>Background/Aims: Rehabilitation of the bilaterally paralyzed human larynx remains a complex clinical problem. Conventional treatment generally involves surgical enlargement of the compromised airway, but often with resultant dysphonia and risk of aspiration. In this retrospective study, we compared one such treatment, posterior cordotomy, with unilateral laryngeal pacing: reanimation of vocal fold opening by functional electrical stimulation of the posterior cricoarytenoid muscle. Methods: Postoperative peak inspiratory flow (PIF) values and overall voice grade ratings were compared between the two surgical groups, and pre- and postoperative PIF were compared within the pacing group. Results: There were 5 patients in the unilateral pacing group and 12 patients in the unilateral cordotomy group. Within the pacing group, postoperative PIF values were significantly improved from preoperative PIF values (p = 0.04) without a significant effect on voice (grade; p = 0.62). Within the pacing group, the mean postoperative PIF value was significantly higher than that in the cordotomy group (p = 0.05). Also, the mean postoperative overall voice grade values in the pacing group were significantly lower (better) than those of the cordotomy group (p = 0.03). Conclusion: Unilateral pacing appears to be an effective treatment superior to posterior cordotomy with respect to postoperative ventilation and voice outcome measures.</description><identifier>ISSN: 0301-1569</identifier><identifier>EISSN: 1423-0275</identifier><identifier>DOI: 10.1159/000345501</identifier><identifier>PMID: 23736349</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Adult ; Aged ; Cordotomy - methods ; Dysphonia - physiopathology ; Dysphonia - surgery ; Dysphonia - therapy ; Female ; Humans ; Larynx ; Larynx - physiopathology ; Male ; Middle Aged ; Original Paper ; Otolaryngology ; Pacemaker, Artificial ; Paralysis ; Pulmonary Ventilation ; Retrospective Studies ; Treatment Outcome ; Ventilation ; Vocal Cord Paralysis - physiopathology ; Vocal Cord Paralysis - surgery ; Vocal Cord Paralysis - therapy ; Voice - physiology</subject><ispartof>O.R.L. Journal for oto-rhino-laryngology and its related specialties, 2013-01, Vol.75 (2), p.68-73</ispartof><rights>2013 S. Karger AG, Basel</rights><rights>Copyright © 2013 S. Karger AG, Basel.</rights><rights>Copyright (c) 2013 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c518t-9366e3e9a4ffe9ff3631ed90b268134c80cde2107416c8f6f3ae3b130e7701273</citedby><cites>FETCH-LOGICAL-c518t-9366e3e9a4ffe9ff3631ed90b268134c80cde2107416c8f6f3ae3b130e7701273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23736349$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Yike</creatorcontrib><creatorcontrib>Pearce, Elizabeth C.</creatorcontrib><creatorcontrib>Mainthia, Rajshri</creatorcontrib><creatorcontrib>Athavale, Sanjay M.</creatorcontrib><creatorcontrib>Dang, Jennifer</creatorcontrib><creatorcontrib>Ashmead, Daniel H.</creatorcontrib><creatorcontrib>Garrett, C. Gaelyn</creatorcontrib><creatorcontrib>Rousseau, Bernard</creatorcontrib><creatorcontrib>Billante, Cheryl R.</creatorcontrib><creatorcontrib>Zealear, David L.</creatorcontrib><title>Comparison of Ventilation and Voice Outcomes between Unilateral Laryngeal Pacing and Unilateral Cordotomy for the Treatment of Bilateral Vocal Fold Paralysis</title><title>O.R.L. Journal for oto-rhino-laryngology and its related specialties</title><addtitle>ORL</addtitle><description>Background/Aims: Rehabilitation of the bilaterally paralyzed human larynx remains a complex clinical problem. Conventional treatment generally involves surgical enlargement of the compromised airway, but often with resultant dysphonia and risk of aspiration. In this retrospective study, we compared one such treatment, posterior cordotomy, with unilateral laryngeal pacing: reanimation of vocal fold opening by functional electrical stimulation of the posterior cricoarytenoid muscle. Methods: Postoperative peak inspiratory flow (PIF) values and overall voice grade ratings were compared between the two surgical groups, and pre- and postoperative PIF were compared within the pacing group. Results: There were 5 patients in the unilateral pacing group and 12 patients in the unilateral cordotomy group. Within the pacing group, postoperative PIF values were significantly improved from preoperative PIF values (p = 0.04) without a significant effect on voice (grade; p = 0.62). Within the pacing group, the mean postoperative PIF value was significantly higher than that in the cordotomy group (p = 0.05). Also, the mean postoperative overall voice grade values in the pacing group were significantly lower (better) than those of the cordotomy group (p = 0.03). Conclusion: Unilateral pacing appears to be an effective treatment superior to posterior cordotomy with respect to postoperative ventilation and voice outcome measures.</description><subject>Adult</subject><subject>Aged</subject><subject>Cordotomy - methods</subject><subject>Dysphonia - physiopathology</subject><subject>Dysphonia - surgery</subject><subject>Dysphonia - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Larynx</subject><subject>Larynx - physiopathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original Paper</subject><subject>Otolaryngology</subject><subject>Pacemaker, Artificial</subject><subject>Paralysis</subject><subject>Pulmonary Ventilation</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Ventilation</subject><subject>Vocal Cord Paralysis - physiopathology</subject><subject>Vocal Cord Paralysis - surgery</subject><subject>Vocal Cord Paralysis - therapy</subject><subject>Voice - physiology</subject><issn>0301-1569</issn><issn>1423-0275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkU1vEzEQhi0EomnhwB0hS72Uw4I_9ssXJIgoIEUKQm2uluMdpy67drA3oPwY_isTUlYFcbE9nmfeeUdDyDPOXnFeqdeMMVlWFeMPyIyXQhZMNNVDMmOS8YJXtTohpznfIlaJtnlMToRsZC1LNSM_53HYmuRzDDQ6uoIw-t6MHkMTOrqK3gJd7kYbB8h0DeMPgECvwwGCZHq6MGkfNoCvz8b6sPlddi8_j6mLYxz21MVExxugVwnMOGCjQ8N3E7iKFs_L2HeohB_77PMT8siZPsPTu_uMXF--v5p_LBbLD5_mbxeFrXg7FkrWNUhQpnQOlHM4G4dOsbWoWy5L2zLbgeCsKXltW1c7aUCuuWTQNIyLRp6RN0fd7W49QGfRHDrQ2-QHHE9H4_XfmeBv9CZ-17JRLatrFLi4E0jx2w7yqAefLfS9CRB3WfOScaZEyxSi5_-gt3GXAo6HFG8bgSYFUi-PlE0x5wRuMsOZPixdT0tH9sV99xP5Z8sIPD8CX03aQJqAqf78v-nll8WR0NvOyV9-nL5r</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Li, Yike</creator><creator>Pearce, Elizabeth C.</creator><creator>Mainthia, Rajshri</creator><creator>Athavale, Sanjay M.</creator><creator>Dang, Jennifer</creator><creator>Ashmead, Daniel H.</creator><creator>Garrett, C. Gaelyn</creator><creator>Rousseau, Bernard</creator><creator>Billante, Cheryl R.</creator><creator>Zealear, David L.</creator><general>S. 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Gaelyn ; Rousseau, Bernard ; Billante, Cheryl R. ; Zealear, David L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c518t-9366e3e9a4ffe9ff3631ed90b268134c80cde2107416c8f6f3ae3b130e7701273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Cordotomy - methods</topic><topic>Dysphonia - physiopathology</topic><topic>Dysphonia - surgery</topic><topic>Dysphonia - therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Larynx</topic><topic>Larynx - physiopathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original Paper</topic><topic>Otolaryngology</topic><topic>Pacemaker, Artificial</topic><topic>Paralysis</topic><topic>Pulmonary Ventilation</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Ventilation</topic><topic>Vocal Cord Paralysis - physiopathology</topic><topic>Vocal Cord Paralysis - surgery</topic><topic>Vocal Cord Paralysis - therapy</topic><topic>Voice - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Yike</creatorcontrib><creatorcontrib>Pearce, Elizabeth C.</creatorcontrib><creatorcontrib>Mainthia, Rajshri</creatorcontrib><creatorcontrib>Athavale, Sanjay M.</creatorcontrib><creatorcontrib>Dang, Jennifer</creatorcontrib><creatorcontrib>Ashmead, Daniel H.</creatorcontrib><creatorcontrib>Garrett, C. 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Journal for oto-rhino-laryngology and its related specialties</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Yike</au><au>Pearce, Elizabeth C.</au><au>Mainthia, Rajshri</au><au>Athavale, Sanjay M.</au><au>Dang, Jennifer</au><au>Ashmead, Daniel H.</au><au>Garrett, C. Gaelyn</au><au>Rousseau, Bernard</au><au>Billante, Cheryl R.</au><au>Zealear, David L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Ventilation and Voice Outcomes between Unilateral Laryngeal Pacing and Unilateral Cordotomy for the Treatment of Bilateral Vocal Fold Paralysis</atitle><jtitle>O.R.L. Journal for oto-rhino-laryngology and its related specialties</jtitle><addtitle>ORL</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>75</volume><issue>2</issue><spage>68</spage><epage>73</epage><pages>68-73</pages><issn>0301-1569</issn><eissn>1423-0275</eissn><abstract>Background/Aims: Rehabilitation of the bilaterally paralyzed human larynx remains a complex clinical problem. Conventional treatment generally involves surgical enlargement of the compromised airway, but often with resultant dysphonia and risk of aspiration. In this retrospective study, we compared one such treatment, posterior cordotomy, with unilateral laryngeal pacing: reanimation of vocal fold opening by functional electrical stimulation of the posterior cricoarytenoid muscle. Methods: Postoperative peak inspiratory flow (PIF) values and overall voice grade ratings were compared between the two surgical groups, and pre- and postoperative PIF were compared within the pacing group. Results: There were 5 patients in the unilateral pacing group and 12 patients in the unilateral cordotomy group. Within the pacing group, postoperative PIF values were significantly improved from preoperative PIF values (p = 0.04) without a significant effect on voice (grade; p = 0.62). Within the pacing group, the mean postoperative PIF value was significantly higher than that in the cordotomy group (p = 0.05). Also, the mean postoperative overall voice grade values in the pacing group were significantly lower (better) than those of the cordotomy group (p = 0.03). Conclusion: Unilateral pacing appears to be an effective treatment superior to posterior cordotomy with respect to postoperative ventilation and voice outcome measures.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>23736349</pmid><doi>10.1159/000345501</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | O.R.L. Journal for oto-rhino-laryngology and its related specialties, 2013-01, Vol.75 (2), p.68-73 |
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| source | Karger Journals; MEDLINE; Alma/SFX Local Collection; Karger:Jisc Collections:ORL, Ophthalmology, Dental Medicine, Obstetrics, Gynecology and Psychology, Psychiatry Archive Collection (2012-2112) |
| subjects | Adult Aged Cordotomy - methods Dysphonia - physiopathology Dysphonia - surgery Dysphonia - therapy Female Humans Larynx Larynx - physiopathology Male Middle Aged Original Paper Otolaryngology Pacemaker, Artificial Paralysis Pulmonary Ventilation Retrospective Studies Treatment Outcome Ventilation Vocal Cord Paralysis - physiopathology Vocal Cord Paralysis - surgery Vocal Cord Paralysis - therapy Voice - physiology |
| title | Comparison of Ventilation and Voice Outcomes between Unilateral Laryngeal Pacing and Unilateral Cordotomy for the Treatment of Bilateral Vocal Fold Paralysis |
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