Expression and Functional Characterization of Retinoic Acid-Inducible Gene-I-Like Receptors of Mast Cells in Response to Viral Infection

To investigate the precise mechanisms of virus recognition by mast cells, the expression and functional characteristics of virus recognition receptors that lead to mast cell activation were investigated. Our results suggest that mast cells are partly responsible for the early in vivo production of a...

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Veröffentlicht in:	Journal of innate immunity 2013-01, Vol.5 (2), p.163-173
Hauptverfasser:	Fukuda, Minoru, Ushio, Hiroko, Kawasaki, Junko, Niyonsaba, Francois, Takeuchi, Mizuho, Baba, Tadashi, Hiramatsu, Keiichi, Okumura, Ko, Ogawa, Hideoki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow - immunology Cell Degranulation - genetics Cell Degranulation - immunology Cells, Cultured Cytokines - metabolism DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism Gene Expression Regulation Immunity, Innate - genetics Interferon-Induced Helicase, IFIH1 Mast Cells - immunology Mast Cells - virology Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mice, Inbred C57BL Mice, Knockout Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Research Article RNA, Small Interfering - genetics RNA, Viral - immunology Toll-Like Receptor 3 - genetics Toll-Like Receptor 3 - metabolism Vesicular Stomatitis - immunology Vesiculovirus - immunology
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