Chromosome Breakage in Human Preimplantation Embryos from Carriers of Structural Chromosomal Abnormalities in Relation to Fragile Sites, Maternal Age, and Poor Sperm Factors

Chromosome breakage is a fairly widespread phenomenon in preimplantation embryos affecting at least 10% of day 3 cleavage stage embryos. It may be detected during preimplantation genetic diagnosis (PGD). For carriers of structural chromosomal abnormalities, PGD involves the removal and testing of si...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cytogenetic and genome research 2012-01, Vol.136 (1), p.21-29
Hauptverfasser:	Xanthopoulou, L., Ghevaria, H., Mantzouratou, A., Serhal, P., Doshi, A., Delhanty, J.D.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Blastocyst - physiology Blastocyst - ultrastructure Blastomeres - metabolism Blastomeres - pathology Chromosome Breakage Chromosome Fragile Sites Embryo Transfer - methods Female Follow-Up Studies Genetic Testing Heterozygote Humans Male Maternal Age Middle Aged Original Article Pregnancy Preimplantation Diagnosis - methods Reproductive History Sex Factors Spermatozoa - metabolism Spermatozoa - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!