Phosphoglycerate Kinase 1 Promoting Tumor Progression and Metastasis in Gastric Cancer - Detected in a Tumor Mouse Model Using Positron Emission Tomography/Magnetic Resonance Imaging

Background/Aims: Tumor dissemination is frequent in gastric cancer and implies a poor prognosis. Cure is only achievable provided an accurate staging is performed at primary diagnosis. In previous studies we were able to show a relevant impact of increased phosphoglycerate kinase 1 expression (PGK1;...

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Veröffentlicht in:	Cellular physiology and biochemistry 2010-01, Vol.26 (2), p.147-154
Hauptverfasser:	Zieker, Derek, Königsrainer, Ingmar, Weinreich, Jürgen, Beckert, Stefan, Glatzle, Jörg, Nieselt, Kay, Bühler, Sarah, Löffler, Markus, Gaedcke, Jochen, Northoff, Hinnak, Mannheim, Julia G., Wiehr, Stefan, Pichler, Bernd J., von Weyhern, Claus, Brücher, Björn L.D.M., Königsrainer, Alfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Disease Models, Animal Disease Progression Female Humans Immunohistochemistry Magnetic Resonance Imaging Mice Mice, Nude Neoplasm Metastasis Original Paper Phosphoglycerate Kinase - genetics Phosphoglycerate Kinase - metabolism Positron-Emission Tomography Prognosis Stomach Neoplasms - diagnostic imaging Stomach Neoplasms - enzymology Stomach Neoplasms - pathology
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