Mitoxantrone Does Not Restore the Impaired Suppressive Function of Natural Regulatory T Cells in Patients Suffering from Multiple Sclerosis

CD4+CD25+ regulatory T (T reg ) cells play a major role in controlling autoimmunity by suppressing self-reactive T cells. Multiple sclerosis (MS) is an inflammatory demyelinating disorder of the central nervous system, where T cells are of major importance. T reg cell frequency and function are pote...

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Veröffentlicht in:	European neurology 2009-01, Vol.61 (1), p.27-32
Hauptverfasser:	Putzki, Norman, Kumar, Manoj, Kreuzfelder, Ernst, Grosse-Wilde, Hans, Diener, H.C., Limmroth, Volker
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Paper
Online-Zugang:	Volltext
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