Distinct Functional Roles for the Menkes and Wilson Copper Translocating P-type ATPases in Human Placental Cells

Background/Aims: The copper transporting ATPases, Menkes (ATP7A; MNK) and Wilson (ATP7B; WND) are essential for normal copper transport in the human body. The placenta is the key organ in copper supply to the fetus during pregnancy and it is one of the few organs in the body to express both of the A...

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Veröffentlicht in:	Cellular physiology and biochemistry 2007-01, Vol.20 (6), p.1073-1084
Hauptverfasser:	Hardman, Belinda, Michalczyk, Agnes, Greenough, Mark, Camakaris, James, Mercer, JJulian, Ackland, Leigh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Biological Transport Cation Transport Proteins - genetics Cation Transport Proteins - metabolism Cell Line Cell Membrane - metabolism Cell Polarity Copper - metabolism Copper-transporting ATPases Female Gene Expression Gene Expression Regulation Humans Original Paper Placenta - cytology Placenta - enzymology Placenta - metabolism Pregnancy Protein-Lysine 6-Oxidase - metabolism RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Superoxide Dismutase - metabolism Transfection
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