Isoforms of the Major Peanut Allergen Ara h 2: IgE Binding in Children with Peanut Allergy

Background: The major peanut allergen Ara h 2 consists of two isoforms, namely Ara h 2.0101 and Ara h 2.0201. The recently identified Ara h 2.0201 isoform contains an extra 12 amino acids including an extra copy of the reported immunodominant epitope DPYSPS. This study aimed to evaluate the IgE bind...

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Veröffentlicht in:	International archives of allergy and immunology 2004-10, Vol.135 (2), p.101-107
Hauptverfasser:	Hales, Belinda J., Bosco, Anthony, Mills, Kristina L., Hazell, Lee A., Loh, Richard, Holt, Patrick G., Thomas, Wayne R.
Format:	Artikel
Sprache:	eng
Schlagworte:	2S Albumins, Plant Adolescent Allergies Amino Acid Sequence Amino acids Antibody Specificity - immunology Antigens, Plant Arachis - immunology Binding, Competitive Biological and medical sciences Child Child, Preschool Children & youth Fundamental and applied biological sciences. Psychology Fundamental immunology Glycoproteins - chemistry Glycoproteins - genetics Glycoproteins - immunology Humans Immunoglobulin E - immunology Immunopathology Infant Medical sciences Molecular Sequence Data Original Paper Peanut Hypersensitivity - immunology Peanuts Plant Proteins Polymerase Chain Reaction Polymorphism, Genetic Protein Isoforms - chemistry Protein Isoforms - genetics Protein Isoforms - immunology
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