Overexpression of Cyclin D1 Is Associated with Poor Survival in Epithelial Ovarian Cancer

Objective: In order to assess the prognostic role of the cell-cycle regulator cyclin D1 in epithelial ovarian cancer, 70 patients have been studied during an observation period of 8 years. Methods: The cyclin D1 protein content was analyzed by Western blotting, and classed as negative, positive and...

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Veröffentlicht in:	Oncology 2004-01, Vol.66 (4), p.310-315
Hauptverfasser:	Barbieri, Federica, Lorenzi, Paola, Ragni, Nicola, Schettini, Gennaro, Bruzzo, Cristina, Pedullà, Francesco, Alama, Angela
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Biological and medical sciences Biomarkers, Tumor - analysis Blotting, Western Carcinoma - chemistry Carcinoma - mortality Carcinoma - pathology Cell cycle Cyclin D1 - analysis Female Female genital diseases Follow-Up Studies Gene expression Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Laboratory/Clinical Translational Research Medical sciences Middle Aged Oncology Ovarian cancer Ovarian Neoplasms - chemistry Ovarian Neoplasms - mortality Ovarian Neoplasms - pathology Predictive Value of Tests Prognosis Proteins Survival Analysis Tumors Up-Regulation
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