A New MF59-Adjuvanted Influenza Vaccine Enhances the Immune Response in the Elderly with Chronic Diseases: Results from an Immunogenicity Meta-Analysis

Background: The elderly are at a higher risk of morbidity and mortality associated with influenza infection than younger adults, but get less protection from conventional vaccination. Objective: We conducted a meta-analysis of all available data from clinical trials in the elderly on a recently intr...

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Veröffentlicht in:	Gerontology (Basel) 2003-05, Vol.49 (3), p.177-184
Hauptverfasser:	Banzhoff, Angelika, Nacci, Pantaleo, Podda, Audino
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - therapeutic use Aged Aged, 80 and over Applied microbiology Biological and medical sciences Chronic Disease - drug therapy Clinical Section Clinical Trials, Phase II as Topic Clinical Trials, Phase III as Topic Female Fundamental and applied biological sciences. Psychology Hemagglutination Inhibition Tests Humans Immunity - drug effects Influenza Vaccines - immunology Influenza Vaccines - therapeutic use Male Microbiology Polysorbates - therapeutic use Prospective Studies Randomized Controlled Trials as Topic Single-Blind Method Squalene - immunology Squalene - therapeutic use Systematic review Treatment Outcome Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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