Neoadjuvant Treatment with Weekly High-Dose 5-Fluorouracil as 24-Hour Infusion, Folinic Acid and Oxaliplatin in Patients with Primary Resectable Liver Metastases of Colorectal Cancer

Purpose: To evaluate the efficacy and safety of neoadjuvant treatment comprising weekly high-dose 5-fluorouracil (5-FU) as a 24-hour infusion, folinic acid (FA) and biweekly oxaliplatin (L-OHP), followed by metastatic resection in patients with primarily resectable liver metastases of colorectal can...

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Veröffentlicht in:	Oncology 2003-01, Vol.64 (2), p.131-138
Hauptverfasser:	Wein, A., Riedel, C., Brückl, W., Merkel, S., Ott, R., Hanke, B., Baum, U., Fuchs, F., Günther, K., Reck, T., Papadopoulos, T., Hahn, E.G., Hohenberger, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antimetabolites, Antineoplastic - administration & dosage Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Chemotherapy, Adjuvant Clinical Study Colorectal Neoplasms - pathology Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Drug Administration Schedule Female Fluorouracil - administration & dosage Humans Leucovorin - administration & dosage Liver Neoplasms - diagnostic imaging Liver Neoplasms - drug therapy Liver Neoplasms - secondary Liver Neoplasms - surgery Male Medical sciences Middle Aged Neoadjuvant Therapy - methods Organoplatinum Compounds - administration & dosage Pharmacology. Drug treatments Survival Analysis Tomography, X-Ray Computed Treatment Outcome
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