Hypersensitivity Reactions to Carboplatin Administration Are Common but Not Always Severe: A 10-Year Experience

We have retrospectively evaluated and characterized the hypersensitivity reactions associated with carboplatin administration in ovarian cancer patients treated mainly on an outpatient basis at the Laikon Hospital from 1988 to 1998. A total of 240 patients, who had never been exposed to platinum com...

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Veröffentlicht in:	Oncology 2001-01, Vol.61 (2), p.129-133
Hauptverfasser:	Polyzos, Aristidis, Tsavaris, Nicolas, Kosmas, Christos, Arnaouti, Theodora, Kalahanis, Nicolas, Tsigris, Christos, Giannopoulos, Athanasios, Karatzas, Gabriel, Giannikos, Lambros, Sfikakis, Petros P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bronchial Spasm - chemically induced Carboplatin - administration & dosage Carboplatin - adverse effects Clinical Study Combined Modality Therapy Cyclophosphamide - administration & dosage Cyclophosphamide - adverse effects Drug Hypersensitivity - epidemiology Drug Hypersensitivity - etiology Drug toxicity and drugs side effects treatment Edema - chemically induced Erythema - chemically induced Female Greece - epidemiology Humans Hypertension - chemically induced Hypotension - chemically induced Injections, Intraperitoneal Injections, Intravenous Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Ovarian Neoplasms - complications Ovarian Neoplasms - drug therapy Ovarian Neoplasms - surgery Paclitaxel - administration & dosage Paclitaxel - adverse effects Pharmacology. Drug treatments Pruritus - chemically induced Retrospective Studies Tachycardia - chemically induced
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