Hydrogen Peroxide Reverses IL-5 Afforded Eosinophil Survival and Promotes Constitutive Human Eosinophil Apoptosis

Background: Eosinophils play a central role in the induction and perpetuation of allergic inflammatory responses. The present study was performed to investigate the effects of reactive oxygen intermediates on constitutive apoptosis as well as on interleukin (IL)-5 afforded human eosinophil survival....

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Veröffentlicht in:	International archives of allergy and immunology 2002-01, Vol.127 (1), p.73-78
Hauptverfasser:	Kankaanranta, Hannu, Giembycz, Mark A., Barnes, Peter J., Haddad, El-Bdaoui, Saarelainen, Seppo, Zhang, Xianzhi, Moilanen, Eeva, Lindsay, Mark A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases Apoptosis - drug effects Apoptosis - physiology Biological and medical sciences Catalase - metabolism Cells, Cultured Eosinophils - drug effects Eosinophils - physiology fas Receptor - metabolism General aspects Humans Hydrogen Peroxide - pharmacology Immunopathology Interleukin-5 - physiology Medical sciences Original Paper
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