The Lung in Diabetes mellitus

Sorry, there is no abstract. Read the first few lines of the text instead! Microangiopathy is a ubiquitous phenomenon in diabetes mellitus. Increased non-enzymatic glycation of proteins and peptides of the extracellular matrix and of the serum at chronic high circulating glucose levels plays a central role in its pathogenesis [1-4]. The non-enzymatic glycation leads probably in all organs to an extracellular accumulation of advanced glycolated end products (AGE). The accumulation of AGE in vessel walls is enhanced by high blood pressure [5]. AGE can be demonstrated in tissues by immunohistochemistry [6-8].