Radical Cystectomy for Invasive Bladder Cancer: Contemporary Results and Remaining Controversies
The impact of stage progression of superficial cancer to invasive disease is profound. However, the optimal–timed management of invasive bladder cancer is still controversial. Pelvic lymph node dissection and radical cystectomy are considered to be the optimal therapy regarding local tumor control a...
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| Veröffentlicht in: | European urology 2000-08, Vol.38 (2), p.121-130 |
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| container_title | European urology |
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| creator | Gschwend, Jürgen E. Fair, William R. Vieweg, Johannes |
| description | The impact of stage progression of superficial cancer to invasive disease is profound. However, the optimal–timed management of invasive bladder cancer is still controversial. Pelvic lymph node dissection and radical cystectomy are considered to be the optimal therapy regarding local tumor control and ultimate cure of cancer, whereas chemotherapy offers the only viable but limited option for patients with distant metastasis or locally advanced disease. Identification of conventional and molecular prognostic factors to predict cancer–specific survival following radical cystectomy is one important step to identify candidates that may benefit from early cystectomy or adjunct chemotherapy. With this background, the results of historic and contemporary radical cystectomy series for carcinoma of the bladder are reviewed. |
| doi_str_mv | 10.1159/000020268 |
| format | Article |
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However, the optimal–timed management of invasive bladder cancer is still controversial. Pelvic lymph node dissection and radical cystectomy are considered to be the optimal therapy regarding local tumor control and ultimate cure of cancer, whereas chemotherapy offers the only viable but limited option for patients with distant metastasis or locally advanced disease. Identification of conventional and molecular prognostic factors to predict cancer–specific survival following radical cystectomy is one important step to identify candidates that may benefit from early cystectomy or adjunct chemotherapy. With this background, the results of historic and contemporary radical cystectomy series for carcinoma of the bladder are reviewed.</description><subject>Biological and medical sciences</subject><subject>Cystectomy</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Metastasis</subject><subject>Neoplasm Staging</subject><subject>Neoplasms, Second Primary - epidemiology</subject><subject>Prognosis</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Reproducibility of Results</subject><subject>Review</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the urinary system</subject><subject>Survival Rate</subject><subject>Urethral Neoplasms - surgery</subject><subject>Urinary Bladder Neoplasms - mortality</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Urinary Bladder Neoplasms - surgery</subject><issn>0302-2838</issn><issn>1873-7560</issn><issn>1421-993X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0M1LwzAYBvAgipvTg2dBiojgoZqPtmm9aZk6GAjDnWuavhnRfsykHey_N1vnx8FcEnh-vC95EDol-IaQMLnF7lBMo3gPDUnMmc_DCO-jIWaY-jRm8QAdWfvuFAsTdogGBMdJiDEZoreZKLQUpZeubQuybaq1pxrjTeqVsHoF3kMpigKMl4pagrnz0qZuoVo2Rpi1NwPbla31RF24dyV0revFlphmBcZqsMfoQInSwsnuHqH54_g1ffanL0-T9H7qSxby1md5THPgLAAQMgeJAxoWknKuVAFcRUkQigDLXEaEJOAC4CTnUQKcxiqJgY3QVT93aZrPDmybVdpKKEtRQ9PZjBPKeECpg9c9lKax1oDKlkZX7jcZwdmmzuynTmfPd0O7vILij-z7c-ByB4R1LSrjWtL21wWEhsFm51nPPoRZgPnJv7dc_JuO57MtyJaFYl9y0ZHj</recordid><startdate>20000801</startdate><enddate>20000801</enddate><creator>Gschwend, Jürgen E.</creator><creator>Fair, William R.</creator><creator>Vieweg, Johannes</creator><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000801</creationdate><title>Radical Cystectomy for Invasive Bladder Cancer: Contemporary Results and Remaining Controversies</title><author>Gschwend, Jürgen E. ; Fair, William R. ; Vieweg, Johannes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-3b82be734eeacbec0425dc277ffde7f6945a40cbc6119ec27e71b769e728f98e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Biological and medical sciences</topic><topic>Cystectomy</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Metastasis</topic><topic>Neoplasm Staging</topic><topic>Neoplasms, Second Primary - epidemiology</topic><topic>Prognosis</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Reproducibility of Results</topic><topic>Review</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the urinary system</topic><topic>Survival Rate</topic><topic>Urethral Neoplasms - surgery</topic><topic>Urinary Bladder Neoplasms - mortality</topic><topic>Urinary Bladder Neoplasms - pathology</topic><topic>Urinary Bladder Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gschwend, Jürgen E.</creatorcontrib><creatorcontrib>Fair, William R.</creatorcontrib><creatorcontrib>Vieweg, Johannes</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gschwend, Jürgen E.</au><au>Fair, William R.</au><au>Vieweg, Johannes</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radical Cystectomy for Invasive Bladder Cancer: Contemporary Results and Remaining Controversies</atitle><jtitle>European urology</jtitle><addtitle>Eur Urol</addtitle><date>2000-08-01</date><risdate>2000</risdate><volume>38</volume><issue>2</issue><spage>121</spage><epage>130</epage><pages>121-130</pages><issn>0302-2838</issn><eissn>1873-7560</eissn><eissn>1421-993X</eissn><coden>EUURAV</coden><abstract>The impact of stage progression of superficial cancer to invasive disease is profound. 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| fulltext | fulltext |
| identifier | ISSN: 0302-2838 |
| ispartof | European urology, 2000-08, Vol.38 (2), p.121-130 |
| issn | 0302-2838 1873-7560 1421-993X |
| language | eng |
| recordid | cdi_crossref_primary_10_1159_000020268 |
| source | Karger Journals; MEDLINE |
| subjects | Biological and medical sciences Cystectomy Humans Lymphatic Metastasis Male Medical sciences Neoplasm Invasiveness Neoplasm Metastasis Neoplasm Staging Neoplasms, Second Primary - epidemiology Prognosis Prostatic Neoplasms - pathology Reproducibility of Results Review Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Survival Rate Urethral Neoplasms - surgery Urinary Bladder Neoplasms - mortality Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - surgery |
| title | Radical Cystectomy for Invasive Bladder Cancer: Contemporary Results and Remaining Controversies |
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