Linalool Alleviates A β 42-Induced Neurodegeneration via Suppressing ROS Production and Inflammation in Fly and Rat Models of Alzheimer's Disease

Terpenes are vital metabolites found in various plants and animals and known to be beneficial in the treatment of various diseases. Previously, our group identified terpenes that increased the survival of Alzheimer's disease (AD) model flies expressing human amyloid (A ) and identified linalool...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2021, Vol.2021 (1), p.8887716
Hauptverfasser:	Yuan, Chunyu, Shin, Myeongcheol, Park, Youngjae, Choi, Byoungyun, Jang, Seokhui, Lim, Chaejin, Yun, Hye Sup, Lee, Im-Soon, Won, So-Yoon, Cho, Kyoung Sang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclic Monoterpenes - pharmacology Alzheimer Disease - drug therapy Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer Disease - pathology Amyloid beta-Peptides - genetics Amyloid beta-Peptides - metabolism Animals Disease Models, Animal Drosophila melanogaster Peptide Fragments - genetics Peptide Fragments - metabolism Rats Rats, Sprague-Dawley Reactive Oxygen Species - metabolism
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