CD4 + CD45RA - FOXP3 low Regulatory T Cells as Potential Biomarkers of Disease Activity in Systemic Lupus Erythematosus Brazilian Patients

Heren, we analyzed Treg cells as potential biomarkers of disease activity in systemic lupus erythematosus (SLE) patients. Peripheral blood mononuclear cells from 30 SLE patients (15 active: SLEDAI > 6/15 SLE remission: SLEDAI< 6) and 15 healthy volunteers were purified. Treg immunophenotyping...

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Veröffentlicht in:	BioMed research international 2018-06, Vol.2018, p.3419565-8
Hauptverfasser:	Silva-Neta, Helena L, Brelaz-de-Castro, Maria C A, Chagas, Mardonny B O, Mariz, Henrique A, de Arruda, Rodrigo G, de Vasconcelos, Viviane F, Pereira, Michelly C, Romano, Audrey, Pitta, Ivan R, Marques, Claudia D L, Duarte, Angela L B P, Rêgo, Moacyr J B M, Pitta, Maira G R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers Brazil CD4 Antigens Female Flow Cytometry Forkhead Transcription Factors Humans Interleukin-2 Receptor alpha Subunit Leukocyte Common Antigens Leukocytes, Mononuclear Lupus Erythematosus, Systemic - immunology Male Middle Aged T-Lymphocytes, Regulatory Young Adult
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