Computational Evaluation of 2‐Phenyl‐4 H ‐chromen‐4‐one Analogues as Antihistamines: Potential Histamine N ‐Methyltransferase (HMT) Inhibitors

Abnormal release of histamine, which is present in relatively high concentration in the lungs, causes serious allergic vasoconstriction and anaphylactic manifestation in human beings. In mammals, a major pathway of histamine metabolism in the lungs is mediated by histamine N ‐methyl transferase (HMT...

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Veröffentlicht in:	Journal of chemistry 2009-01, Vol.6 (4), p.1009-1016
Hauptverfasser:	Dave, Shikha S., Rahatgaonkar, Anjali M.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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