Ethanol Alters the Frequency, Amplitude, and Decay Kinetics of Sr 2+ -Supported, Asynchronous NMDAR mEPSCs in Rat Hippocampal Slices

To discriminate between pre- and postsynaptic effects of ethanol on N-methyl-d-aspartate receptor (NMDAR) signaling in hippocampus, we adapted the technique of Sr 2+ substitution to the hippocampal blind slice patch-clamp preparation. Hippocampal slices were isolated from 12- to 20-day-old rats that...

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Veröffentlicht in:Journal of neurophysiology 2004-06, Vol.91 (6), p.2568-2577
Hauptverfasser: Hendricson, Adam W., Sibbald, John R., Morrisett, Richard A.
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Sprache:eng
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