BK-β1 subunit: immunolocalization in the mammalian connecting tubule and its role in the kaliuretic response to volume expansion

Large, Ca 2+ -activated K + channels (BK), comprised of α- and β-subunits, mediate K + secretion during high flow rates in distal nephron segments. Because the BK-β1 subunit enhances Ca 2+ sensitivity of BK in a variety of cells, we determined its role in flow-induced K + secretion and its localizat...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2005-04, Vol.288 (4), p.F846-F854
Hauptverfasser:	Pluznick, Jennifer L., Wei, Peilin, Grimm, P. Richard, Sansom, Steven C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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