Enhanced pressor response to increased CSF sodium concentration and to central ANG I in heterozygous α 2 Na + -K + -ATPase knockout mice

Intracerebroventricular (ICV) infusion of NaCl mimics the effects of a high-salt diet in salt-sensitive hypertension, raising the sodium concentration in the cerebrospinal fluid (CSF [Na]) and subsequently increasing the concentration of an endogenous ouabain-like substance (OLS) in the brain. The O...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2009-05, Vol.296 (5), p.R1427-R1438
Hauptverfasser:	Hou, Xiaohong, Theriault, Steven F., Dostanic-Larson, Iva, Moseley, Amy E., Lingrel, Jerry B, Wu, Hengwei, Dean, Stephanie, Van Huysse, James W.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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