The plateau in the NIRS-derived [HHb] signal near the end of a ramp incremental test does not indicate the upper limit of O 2 extraction in the vastus lateralis
This study aimed to examine, at the level of the active muscles, whether the plateau in oxygen (O ) extraction normally observed near the end of a ramp incremental (RI) exercise test to exhaustion is caused by the achievement of an upper limit in O extraction. Eleven healthy men (27.3 ± 3.0 yr, 81.6...
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| Veröffentlicht in: | American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2017-12, Vol.313 (6), p.R723-R729 |
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| container_title | American journal of physiology. Regulatory, integrative and comparative physiology |
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| creator | Inglis, Erin Calaine Iannetta, Danilo Murias, Juan M |
| description | This study aimed to examine, at the level of the active muscles, whether the plateau in oxygen (O
) extraction normally observed near the end of a ramp incremental (RI) exercise test to exhaustion is caused by the achievement of an upper limit in O
extraction. Eleven healthy men (27.3 ± 3.0 yr, 81.6 ± 8.1 kg, 183.9 ± 6.3 cm) performed a RI cycling test to exhaustion. O
extraction of the vastus lateralis (VL) was measured continuously throughout the test using the near-infrared spectroscopy (NIRS)-derived deoxygenated hemoglobin [HHb] signal. A leg blood flow occlusion was performed at rest (LBF
) and immediately after the RI test (LBF
). The [HHb] values during the resting occlusion (108.1 ± 21.7%; LBF
) and the peak values during exercise (100 ± 0%; [HHb]
) were significantly greater than those observed at baseline (0.84 ± 10.6% at
and 0 ± 0% at
) (
< 0.05). No significant difference was found between LBF
and [HHb]
(
> 0.05) or between the baseline measurements (
> 0.05). [HHb] values at LBF
(130.5 ± 19.7%) were significantly greater than all other time points (
< 0.05). These results support the existence of an O
extraction reserve in the VL muscle at the end of a RI cycling test and suggest that the observed plateau in the [HHb] signal toward the end of a RI test is not representative of an upper limit in O
extraction. |
| doi_str_mv | 10.1152/ajpregu.00261.2017 |
| format | Article |
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) extraction normally observed near the end of a ramp incremental (RI) exercise test to exhaustion is caused by the achievement of an upper limit in O
extraction. Eleven healthy men (27.3 ± 3.0 yr, 81.6 ± 8.1 kg, 183.9 ± 6.3 cm) performed a RI cycling test to exhaustion. O
extraction of the vastus lateralis (VL) was measured continuously throughout the test using the near-infrared spectroscopy (NIRS)-derived deoxygenated hemoglobin [HHb] signal. A leg blood flow occlusion was performed at rest (LBF
) and immediately after the RI test (LBF
). The [HHb] values during the resting occlusion (108.1 ± 21.7%; LBF
) and the peak values during exercise (100 ± 0%; [HHb]
) were significantly greater than those observed at baseline (0.84 ± 10.6% at
and 0 ± 0% at
) (
< 0.05). No significant difference was found between LBF
and [HHb]
(
> 0.05) or between the baseline measurements (
> 0.05). [HHb] values at LBF
(130.5 ± 19.7%) were significantly greater than all other time points (
< 0.05). These results support the existence of an O
extraction reserve in the VL muscle at the end of a RI cycling test and suggest that the observed plateau in the [HHb] signal toward the end of a RI test is not representative of an upper limit in O
extraction.</description><identifier>ISSN: 0363-6119</identifier><identifier>EISSN: 1522-1490</identifier><identifier>DOI: 10.1152/ajpregu.00261.2017</identifier><identifier>PMID: 28931547</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Anaerobic Threshold ; Electromyography ; Exercise - physiology ; Exercise Test - methods ; Exercise Test - statistics & numerical data ; Hemoglobins - metabolism ; Humans ; Leg ; Male ; Oxygen - blood ; Oxygen Consumption - physiology ; Pulmonary Gas Exchange ; Quadriceps Muscle - metabolism ; Spectroscopy, Near-Infrared</subject><ispartof>American journal of physiology. Regulatory, integrative and comparative physiology, 2017-12, Vol.313 (6), p.R723-R729</ispartof><rights>Copyright © 2017 the American Physiological Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c200t-16701b1e7da0dd84c0c7db835a353f73cf88cdec36270be25dfc4769de11d7d93</citedby><cites>FETCH-LOGICAL-c200t-16701b1e7da0dd84c0c7db835a353f73cf88cdec36270be25dfc4769de11d7d93</cites><orcidid>0000-0002-6460-6453</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,3037,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28931547$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Inglis, Erin Calaine</creatorcontrib><creatorcontrib>Iannetta, Danilo</creatorcontrib><creatorcontrib>Murias, Juan M</creatorcontrib><title>The plateau in the NIRS-derived [HHb] signal near the end of a ramp incremental test does not indicate the upper limit of O 2 extraction in the vastus lateralis</title><title>American journal of physiology. Regulatory, integrative and comparative physiology</title><addtitle>Am J Physiol Regul Integr Comp Physiol</addtitle><description>This study aimed to examine, at the level of the active muscles, whether the plateau in oxygen (O
) extraction normally observed near the end of a ramp incremental (RI) exercise test to exhaustion is caused by the achievement of an upper limit in O
extraction. Eleven healthy men (27.3 ± 3.0 yr, 81.6 ± 8.1 kg, 183.9 ± 6.3 cm) performed a RI cycling test to exhaustion. O
extraction of the vastus lateralis (VL) was measured continuously throughout the test using the near-infrared spectroscopy (NIRS)-derived deoxygenated hemoglobin [HHb] signal. A leg blood flow occlusion was performed at rest (LBF
) and immediately after the RI test (LBF
). The [HHb] values during the resting occlusion (108.1 ± 21.7%; LBF
) and the peak values during exercise (100 ± 0%; [HHb]
) were significantly greater than those observed at baseline (0.84 ± 10.6% at
and 0 ± 0% at
) (
< 0.05). No significant difference was found between LBF
and [HHb]
(
> 0.05) or between the baseline measurements (
> 0.05). [HHb] values at LBF
(130.5 ± 19.7%) were significantly greater than all other time points (
< 0.05). These results support the existence of an O
extraction reserve in the VL muscle at the end of a RI cycling test and suggest that the observed plateau in the [HHb] signal toward the end of a RI test is not representative of an upper limit in O
extraction.</description><subject>Adult</subject><subject>Anaerobic Threshold</subject><subject>Electromyography</subject><subject>Exercise - physiology</subject><subject>Exercise Test - methods</subject><subject>Exercise Test - statistics & numerical data</subject><subject>Hemoglobins - metabolism</subject><subject>Humans</subject><subject>Leg</subject><subject>Male</subject><subject>Oxygen - blood</subject><subject>Oxygen Consumption - physiology</subject><subject>Pulmonary Gas Exchange</subject><subject>Quadriceps Muscle - metabolism</subject><subject>Spectroscopy, Near-Infrared</subject><issn>0363-6119</issn><issn>1522-1490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kNtKw0AQhhdRbK2-gBeyL5C6hySbXEpRWygWtF6JhM3upG7Jid1N0bfxUU168GoY5v9mhg-hW0qmlEbsXm5bC5tuSgiL6ZQRKs7QuB-wgIYpOUdjwmMexJSmI3Tl3JYQEvKQX6IRS1JOo1CM0e_6C3BbSg-yw6bGvm9fFq9vgQZrdqDxx3yef2JnNrUscQ3S7iNQa9wUWGIrq7bnlIUKat9HPDiPdQMO143vJ9qofvke6toWLC5NZfwArzDD8O2tVN409en4TjrfOTx8ZGVp3DW6KGTp4OZYJ-j96XE9mwfL1fNi9rAMFCPEBzQWhOYUhJZE6yRURAmdJzySPOKF4KpIEqVB8ZgJkgOLdKFCEacaKNVCp3yC2GGvso1zFoqstaaS9iejJBt0Z0fd2V53NujuobsD1HZ5BfofOfnlf5MDf1w</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Inglis, Erin Calaine</creator><creator>Iannetta, Danilo</creator><creator>Murias, Juan M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-6460-6453</orcidid></search><sort><creationdate>20171201</creationdate><title>The plateau in the NIRS-derived [HHb] signal near the end of a ramp incremental test does not indicate the upper limit of O 2 extraction in the vastus lateralis</title><author>Inglis, Erin Calaine ; Iannetta, Danilo ; Murias, Juan M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c200t-16701b1e7da0dd84c0c7db835a353f73cf88cdec36270be25dfc4769de11d7d93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Anaerobic Threshold</topic><topic>Electromyography</topic><topic>Exercise - physiology</topic><topic>Exercise Test - methods</topic><topic>Exercise Test - statistics & numerical data</topic><topic>Hemoglobins - metabolism</topic><topic>Humans</topic><topic>Leg</topic><topic>Male</topic><topic>Oxygen - blood</topic><topic>Oxygen Consumption - physiology</topic><topic>Pulmonary Gas Exchange</topic><topic>Quadriceps Muscle - metabolism</topic><topic>Spectroscopy, Near-Infrared</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inglis, Erin Calaine</creatorcontrib><creatorcontrib>Iannetta, Danilo</creatorcontrib><creatorcontrib>Murias, Juan M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>American journal of physiology. Regulatory, integrative and comparative physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inglis, Erin Calaine</au><au>Iannetta, Danilo</au><au>Murias, Juan M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The plateau in the NIRS-derived [HHb] signal near the end of a ramp incremental test does not indicate the upper limit of O 2 extraction in the vastus lateralis</atitle><jtitle>American journal of physiology. Regulatory, integrative and comparative physiology</jtitle><addtitle>Am J Physiol Regul Integr Comp Physiol</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>313</volume><issue>6</issue><spage>R723</spage><epage>R729</epage><pages>R723-R729</pages><issn>0363-6119</issn><eissn>1522-1490</eissn><abstract>This study aimed to examine, at the level of the active muscles, whether the plateau in oxygen (O
) extraction normally observed near the end of a ramp incremental (RI) exercise test to exhaustion is caused by the achievement of an upper limit in O
extraction. Eleven healthy men (27.3 ± 3.0 yr, 81.6 ± 8.1 kg, 183.9 ± 6.3 cm) performed a RI cycling test to exhaustion. O
extraction of the vastus lateralis (VL) was measured continuously throughout the test using the near-infrared spectroscopy (NIRS)-derived deoxygenated hemoglobin [HHb] signal. A leg blood flow occlusion was performed at rest (LBF
) and immediately after the RI test (LBF
). The [HHb] values during the resting occlusion (108.1 ± 21.7%; LBF
) and the peak values during exercise (100 ± 0%; [HHb]
) were significantly greater than those observed at baseline (0.84 ± 10.6% at
and 0 ± 0% at
) (
< 0.05). No significant difference was found between LBF
and [HHb]
(
> 0.05) or between the baseline measurements (
> 0.05). [HHb] values at LBF
(130.5 ± 19.7%) were significantly greater than all other time points (
< 0.05). These results support the existence of an O
extraction reserve in the VL muscle at the end of a RI cycling test and suggest that the observed plateau in the [HHb] signal toward the end of a RI test is not representative of an upper limit in O
extraction.</abstract><cop>United States</cop><pmid>28931547</pmid><doi>10.1152/ajpregu.00261.2017</doi><orcidid>https://orcid.org/0000-0002-6460-6453</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0363-6119 |
| ispartof | American journal of physiology. Regulatory, integrative and comparative physiology, 2017-12, Vol.313 (6), p.R723-R729 |
| issn | 0363-6119 1522-1490 |
| language | eng |
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| source | MEDLINE; American Physiological Society; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Anaerobic Threshold Electromyography Exercise - physiology Exercise Test - methods Exercise Test - statistics & numerical data Hemoglobins - metabolism Humans Leg Male Oxygen - blood Oxygen Consumption - physiology Pulmonary Gas Exchange Quadriceps Muscle - metabolism Spectroscopy, Near-Infrared |
| title | The plateau in the NIRS-derived [HHb] signal near the end of a ramp incremental test does not indicate the upper limit of O 2 extraction in the vastus lateralis |
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