Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica

1 Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505; and 2 Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226 In previous reports from this study, measur...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2002-08, Vol.283 (2), p.485-L493
Hauptverfasser:	Porter, Dale W, Millecchia, Lyndell, Robinson, Victor A, Hubbs, Ann, Willard, Patsy, Pack, Donna, Ramsey, Dawn, McLaurin, Jeff, Khan, Amir, Landsittel, Douglas, Teass, Alexander, Castranova, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Animals Bronchoalveolar Lavage Fluid - chemistry Immunohistochemistry Lipid Peroxides - metabolism Luminescent Measurements Lung - drug effects Lung - enzymology Lung - pathology Macrophages, Alveolar - drug effects Macrophages, Alveolar - physiology Male Nitrates - analysis Nitric Oxide - metabolism Nitrites - analysis Pulmonary Alveoli - drug effects Pulmonary Alveoli - metabolism Pulmonary Alveoli - pathology Rats Rats, Inbred F344 Reactive Oxygen Species - metabolism Silicon Dioxide - administration & dosage Silicon Dioxide - pharmacology Superoxide Dismutase - analysis Time Factors Tyrosine - analogs & derivatives Tyrosine - metabolism Zymosan - pharmacology
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