PAR-2 activation, PGE 2 , and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells

The protease-activated receptor-2 (PAR-2) is present on human airway smooth muscle (ASM) cells and can be activated by mast cell tryptase, trypsin, or an activating peptide (AP). Trypsin induced significant increases in PGE 2 release from human ASM cells after 6 and 24 h and also induced cyclooxygen...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2003-09, Vol.285 (3), p.L619-L627
Hauptverfasser:	Chambers, Linda S., Black, Judith L., Ge, Qi, Carlin, Stephen M., Au, Wendy W., Poniris, Maree, Thompson, Joanne, Johnson, Peter R., Burgess, Janette K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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