TGF-β1 in SP-A preparations influence immune suppressive properties of SP-A on human CD4 + T lymphocytes

Surfactant protein A (SP-A) and transforming growth factor-β 1 (TGF-β1) have been shown to modulate the functions of different immune cells and specifically to inhibit T lymphocyte proliferation. The aim of the present study was to elucidate whether the Smad signaling pathway, which is activated by...

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 2006-10, Vol.291 (4), p.L747-L756
Hauptverfasser: Kunzmann, Steffen, Wright, Jo Rae, Steinhilber, Wolfram, Kramer, Boris W., Blaser, Kurt, Speer, Christian P., Schmidt-Weber, Carsten
Format: Artikel
Sprache:eng
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