Caveolin-3 KO disrupts t-tubule structure and decreases t-tubular I Ca density in mouse ventricular myocytes

Caveolin-3 (Cav-3) is a protein that has been implicated in t-tubule formation and function in cardiac ventricular myocytes. In cardiac hypertrophy and failure, Cav-3 expression decreases, t-tubule structure is disrupted, and excitation-contraction coupling is impaired. However, the extent to which...

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