High-resolution visualization of oxygen distribution in the liver in vivo

Microcirculatory failure after stress events results in mismatch in oxygen supply and demand. Determination of tissue oxygen distribution in vivo may help elucidate mechanisms of injury, but present methods have limited resolution. Male Sprague-Dawley rats were anesthetized, prepared for intravital...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2004-01, Vol.286 (1), p.G37-G44
Hauptverfasser:	Paxian, Markus, Keller, Steve A, Cross, Brian, Huynh, Toan T, Clemens, Mark G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspartate Aminotransferases - metabolism Chemical and Drug Induced Liver Injury - metabolism Chemical and Drug Induced Liver Injury - pathology Fluorescence Fluorescent Dyes - toxicity Hemodynamics - drug effects Hemodynamics - physiology Hemorrhage - enzymology Hemorrhage - metabolism L-Lactate Dehydrogenase - metabolism Liver - anatomy & histology Liver - metabolism Liver Circulation - physiology Male Microcirculation - physiology Microscopy, Video NAD - metabolism Oxidation-Reduction Oxygen Consumption - physiology Rats Rats, Sprague-Dawley
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