CFTR inhibition augments NHE3 activity during luminal high CO 2 exposure in rat duodenal mucosa

We hypothesized that the function of duodenocyte apical membrane acid-base transporters are essential for H + absorption from the lumen. We thus examined the effect of inhibition of Na + /H + exchanger-3 (NHE3), cystic fibrosis transmembrane regulator (CFTR), or apical anion exchangers on transmucos...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 2008-06, Vol.294 (6), p.G1318-G1327
Hauptverfasser: Mizumori, Misa, Choi, Yuri, Guth, Paul H., Engel, Eli, Kaunitz, Jonathan D., Akiba, Yasutada
Format: Artikel
Sprache:eng
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