DHT and testosterone, but not DHEA or E 2 , differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells

Prostate cancer is one of the four most common cancers in the United States, affecting one of six men. Increased serum levels of androgens and IGF-I are associated with an augmented risk of prostate cancer. Dihydrotestosterone (DHT) and testosterone (T) stimulate prostate cancer cell growth, develop...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2006-05, Vol.290 (5), p.E952-E960
Hauptverfasser:	Le, Hanh, Arnold, Julia T., McFann, Kimberly K., Blackman, Marc R.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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