PPARα/γ ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly

Peroxisome proliferator-activated receptor (PPAR)α and PPARγ agonists lower lipid accumulation in muscle and liver by different mechanisms. We investigated whether benefits could be achieved on insulin sensitivity and lipid metabolism by the dual PPARα/γ agonist ragaglitazar in high fat-fed rats. Ra...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2003-03, Vol.284 (3), p.E531-E540
Hauptverfasser:	Ye, Ji-Ming, Iglesias, Miguel A., Watson, David G., Ellis, Bronwyn, Wood, Leonie, Jensen, Per Bo, Sørensen, Rikke Veggerby, Larsen, Philip Just, Cooney, Gregory J., Wassermann, Karsten, Kraegen, Edward W.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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