Regulation of H 2 O 2 -induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes

Recent studies have suggested that, in certain cases, necrosis, like apoptosis, may be programmed, involving the activation and inhibition of many signaling pathways. In this study, we examined whether necrosis induced by H 2 O 2 is regulated by signaling pathways in primary hepatocytes. A detailed...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2008-07, Vol.295 (1), p.C50-C63
Hauptverfasser: Saberi, Behnam, Shinohara, Mie, Ybanez, Maria D., Hanawa, Naoko, Gaarde, William A., Kaplowitz, Neil, Han, Derick
Format: Artikel
Sprache:eng
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