Rab5a and rab11a mediate agonist-induced trafficking of protease-activated receptor 2

Departments of Surgery and Physiology, University of California, San Francisco, California 94143-0660 We evaluated the contribution of rab5a and rab11a to trafficking and signaling of protease-activated receptor 2 (PAR2), a receptor for trypsin and tryptase. Agonists stimulated internalization of PA...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2003-05, Vol.284 (5), p.C1319-C1329
Hauptverfasser:	Roosterman, Dirk, Schmidlin, Fabien, Bunnett, Nigel W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Endocytosis - physiology Humans Protein Transport - physiology rab GTP-Binding Proteins - physiology rab5 GTP-Binding Proteins - physiology Rats Receptor, PAR-2 Receptors, Thrombin - agonists Receptors, Thrombin - metabolism Signal Transduction - physiology Tissue Distribution
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