Increased endogenous H 2 S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

Hydrogen sulfide (H 2 S) has recently been identified as a regulator of various physiological events, including vasodilation, angiogenesis, antiapoptotic, and cellular signaling. Endogenously, H 2 S is produced as a metabolite of homocysteine (Hcy) by cystathionine β-synthase (CBS), cystathionine γ-...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2012-07, Vol.303 (1), p.C41-C51
Hauptverfasser:	Sen, Utpal, Sathnur, Pushpakumar B., Kundu, Sourav, Givvimani, Srikanth, Coley, Denise M., Mishra, Paras K., Qipshidze, Natia, Tyagi, Neetu, Metreveli, Naira, Tyagi, Suresh C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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