Effects of α 1D -adrenergic receptors on shedding of biologically active EGF in freshly isolated lacrimal gland epithelial cells

Transactivation of EGF receptors by G protein-coupled receptors is a well-known phenomenon. This process involves the ectodomain shedding of growth factors in the EGF family by matrix metalloproteinases. However, many of these studies employ transformed and/or cultured cells that overexpress labeled...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2006-11, Vol.291 (5), p.C946-C956
Hauptverfasser:	Chen, LiLi, Hodges, Robin R., Funaki, Chika, Zoukhri, Driss, Gaivin, Robert J., Perez, Dianne M., Dartt, Darlene A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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