Development of Gold Coated Superparamagnetic Iron Oxide Nanoparticles for Nitroreductase Delivery

Directed enzyme prodrug therapies (DEPT) currently suffer from inherent problems associated with localising and retaining enzymes at tumours. Superparamagnetic iron oxide nanoparticles (SPION) have been synthesised (≈10 nm) and surface functionalised with gold by direct reduction and by attachment o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cude, Matthew P., Gwenin, Chris D.
Format: Tagungsbericht
Sprache:eng
Online-Zugang:Volltext
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