Development of Gold Coated Superparamagnetic Iron Oxide Nanoparticles for Nitroreductase Delivery
Directed enzyme prodrug therapies (DEPT) currently suffer from inherent problems associated with localising and retaining enzymes at tumours. Superparamagnetic iron oxide nanoparticles (SPION) have been synthesised (≈10 nm) and surface functionalised with gold by direct reduction and by attachment o...
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