Observation of Fine Lung Structure by Ultrahigh-Resolution Optical Coherence Tomography Using 800, 1060, and 1300 nm Supercontinua
Cross-sectional imaging of isolated rat lungs was demonstrated by ultrahigh-resolution optical coherence tomography using supercontinua at 800, 1060, and 1300 nm wavelengths. The detailed structure of the trachea, including cartilage, mucosa, and annular ligaments, were observed clearly. In the imag...
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Veröffentlicht in: | Japanese Journal of Applied Physics 2012-04, Vol.51 (4), p.047001-047001-7 |
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container_title | Japanese Journal of Applied Physics |
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creator | Ishida, Shutaro Nishizawa, Norihiko Kitatsuji, Masashi Ohshima, Hiroyoshi Hasegawa, Yoshinori Matsushima, Miyoko Kawabe, Tsutomu |
description | Cross-sectional imaging of isolated rat lungs was demonstrated by ultrahigh-resolution optical coherence tomography using supercontinua at 800, 1060, and 1300 nm wavelengths. The detailed structure of the trachea, including cartilage, mucosa, and annular ligaments, were observed clearly. In the imaging of visceral pleura and alveoli, when phosphate-buffered saline was instilled into the lung, the penetration depth of imaging was improved, and clear images of the fine structure of the lung, including alveoli, were observed owing to the index-matching effect. The wavelength dependence of the light source was discussed for the observation of fine structure and imaging contrast. |
doi_str_mv | 10.1143/JJAP.51.047001 |
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The detailed structure of the trachea, including cartilage, mucosa, and annular ligaments, were observed clearly. In the imaging of visceral pleura and alveoli, when phosphate-buffered saline was instilled into the lung, the penetration depth of imaging was improved, and clear images of the fine structure of the lung, including alveoli, were observed owing to the index-matching effect. 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The detailed structure of the trachea, including cartilage, mucosa, and annular ligaments, were observed clearly. In the imaging of visceral pleura and alveoli, when phosphate-buffered saline was instilled into the lung, the penetration depth of imaging was improved, and clear images of the fine structure of the lung, including alveoli, were observed owing to the index-matching effect. The wavelength dependence of the light source was discussed for the observation of fine structure and imaging contrast.</abstract><pub>The Japan Society of Applied Physics</pub><doi>10.1143/JJAP.51.047001</doi></addata></record> |
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title | Observation of Fine Lung Structure by Ultrahigh-Resolution Optical Coherence Tomography Using 800, 1060, and 1300 nm Supercontinua |
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