Observation of Fine Lung Structure by Ultrahigh-Resolution Optical Coherence Tomography Using 800, 1060, and 1300 nm Supercontinua

Cross-sectional imaging of isolated rat lungs was demonstrated by ultrahigh-resolution optical coherence tomography using supercontinua at 800, 1060, and 1300 nm wavelengths. The detailed structure of the trachea, including cartilage, mucosa, and annular ligaments, were observed clearly. In the imag...

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Veröffentlicht in:Japanese Journal of Applied Physics 2012-04, Vol.51 (4), p.047001-047001-7
Hauptverfasser: Ishida, Shutaro, Nishizawa, Norihiko, Kitatsuji, Masashi, Ohshima, Hiroyoshi, Hasegawa, Yoshinori, Matsushima, Miyoko, Kawabe, Tsutomu
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container_issue 4
container_start_page 047001
container_title Japanese Journal of Applied Physics
container_volume 51
creator Ishida, Shutaro
Nishizawa, Norihiko
Kitatsuji, Masashi
Ohshima, Hiroyoshi
Hasegawa, Yoshinori
Matsushima, Miyoko
Kawabe, Tsutomu
description Cross-sectional imaging of isolated rat lungs was demonstrated by ultrahigh-resolution optical coherence tomography using supercontinua at 800, 1060, and 1300 nm wavelengths. The detailed structure of the trachea, including cartilage, mucosa, and annular ligaments, were observed clearly. In the imaging of visceral pleura and alveoli, when phosphate-buffered saline was instilled into the lung, the penetration depth of imaging was improved, and clear images of the fine structure of the lung, including alveoli, were observed owing to the index-matching effect. The wavelength dependence of the light source was discussed for the observation of fine structure and imaging contrast.
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title Observation of Fine Lung Structure by Ultrahigh-Resolution Optical Coherence Tomography Using 800, 1060, and 1300 nm Supercontinua
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