High-Resolution Scanning Tunneling Microscopy and Spectroscopy Studies of Deoxyribonucleic Acid and Fluorescein Isothiocyanate

By using scanning tunneling microscopy (STM), we obtained submolecular-resolution STM images of a single molecule of DNA labeled with the fluorescent dye fluorescein isothiocyanate (FITC). From the observed bias voltage dependences of the topographic height and I – V characteristics of FITC and the...

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Veröffentlicht in:Japanese Journal of Applied Physics 2004-08, Vol.43 (8R), p.5526
Hauptverfasser: Nojima, Yoshihiro, Tanaka, Hiroyuki, Yoshida, Yuhsuke, Kawai, Tomoji
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container_issue 8R
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container_title Japanese Journal of Applied Physics
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creator Nojima, Yoshihiro
Tanaka, Hiroyuki
Yoshida, Yuhsuke
Kawai, Tomoji
description By using scanning tunneling microscopy (STM), we obtained submolecular-resolution STM images of a single molecule of DNA labeled with the fluorescent dye fluorescein isothiocyanate (FITC). From the observed bias voltage dependences of the topographic height and I – V characteristics of FITC and the single molecule DNA, we found that FITC and DNA have different electrical properties. This study shows that STM is useful in the analysis of the properties of molecules by the investigation of a single molecule.
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title High-Resolution Scanning Tunneling Microscopy and Spectroscopy Studies of Deoxyribonucleic Acid and Fluorescein Isothiocyanate
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