6-IODOMETAMECONINE AND 3-IODOMETAHEMIPINIC ACID

6-IODOMETAMECONINE AND 3-IODOMETAHEMIPINIC ACID

6-Iodo-m-meconine has been prepared from m-meconine by several steps and oxidized to 3-iodo-m-hemipinic acid. The orientation of the iodo-m-meconine is based on its conversion to 4, 5, 6-trimethoxyphthalide. The identity reported by Rây and Robinson of the bromo-m-meconine made directly by similar s...

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Veröffentlicht in:Canadian journal of chemistry 1951-06, Vol.29 (6), p.482-489
Hauptverfasser: McRae, J. A, VanOrder, R. B, Griffiths, F. H, Habgood, Thelma Eskin
Format: Artikel
Sprache:eng
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Humans
Noscapine - analogs & derivatives
Old Medline
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container_end_page 489
container_issue 6
container_start_page 482
container_title Canadian journal of chemistry
container_volume 29
creator McRae, J. A
VanOrder, R. B
Griffiths, F. H
Habgood, Thelma Eskin
description 6-Iodo-m-meconine has been prepared from m-meconine by several steps and oxidized to 3-iodo-m-hemipinic acid. The orientation of the iodo-m-meconine is based on its conversion to 4, 5, 6-trimethoxyphthalide. The identity reported by Rây and Robinson of the bromo-m-meconine made directly by similar steps from m-meconine with that from 2-bromoveratric acid and formaldehyde could not be confirmed. The former substance has the orientation ascribed to it by Rây and Robinson but the identity and orientation of the latter substance is left in doubt. Attempts to form a substituted diphenyl ether from dimethyl 3-iodo-m-hemipinate and the potassium salt of methyl vanillate failed.
doi_str_mv 10.1139/v51-057
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subjects Humans
Noscapine - analogs & derivatives
Old Medline
title 6-IODOMETAMECONINE AND 3-IODOMETAHEMIPINIC ACID
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