Synthesis, structure, and pharmacological evaluation of Co(III) complex containing tridentate Schiff base ligand

A Co(III) Schiff base complex with the formula [Co(L) 2 ]Cl · H 2 O ( I ) (L = monoanionic tridentate Schiff base ligand derived from salicylaldehyde and ethylene diamine) has been synthesized and characterized by elemental analysis and spectroscopic techniques. The structure of I was confirmed by s...

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Veröffentlicht in:Russian journal of coordination chemistry 2015-05, Vol.41 (5), p.345-352
Hauptverfasser: Kirubavathy, S. Jone, Velmurugan, R., Karvembu, R., Bhuvanesh, N. S. P., Parameswari, K., Chitra, S.
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container_end_page 352
container_issue 5
container_start_page 345
container_title Russian journal of coordination chemistry
container_volume 41
creator Kirubavathy, S. Jone
Velmurugan, R.
Karvembu, R.
Bhuvanesh, N. S. P.
Parameswari, K.
Chitra, S.
description A Co(III) Schiff base complex with the formula [Co(L) 2 ]Cl · H 2 O ( I ) (L = monoanionic tridentate Schiff base ligand derived from salicylaldehyde and ethylene diamine) has been synthesized and characterized by elemental analysis and spectroscopic techniques. The structure of I was confirmed by single crystal X-ray diffraction studies (CIF file CCDC no. 1009967), which showed the presence of two Schiff base molecules in an octahedral fashion. The complex has been screened for its in vitro antibacterial and anticancer activities. Complex I was found to be more active in anti-microbial and anti-cancer activity than the ligand.
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Chemistry and Materials Science
Inorganic Chemistry
Physical Chemistry
title Synthesis, structure, and pharmacological evaluation of Co(III) complex containing tridentate Schiff base ligand
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