Anaerobic synthesis of succinic acid by recombinant Escherichia coli strains with activated NAD+-reducing pyruvate dehydrogenase complex

Effect of constitutive expression of the aceEF-lpdA operon genes coding for the enzymes of NAD+-reducing pyruvate dehydrogenase complex on the anaerobic production of succinic acid from glucose by recombinant Escherichia coli strains was studied. Basic producer strains were obtained by inactivation...

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Veröffentlicht in:	Applied biochemistry and microbiology 2011-07, Vol.47 (4), p.373-380
Hauptverfasser:	Skorokhodova, A. Yu, Gulevich, A. Yu, Morzhakova, A. A, Shakulov, R. S, Debabov, V. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis bacteriophages Biochemistry Biomedical and Life Sciences Escherichia coli fermentation gene expression glucose Life Sciences Medical Microbiology Microbiology operon pyruvate carboxylase pyruvic acid succinic acid tricarboxylic acid cycle
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