Effect of Passive Administration of Monoclonal Antibodies Recognizing Simian Immunodeficiency Virus (SIV) V2 in CH59-Like Coil/Helical or β-Sheet Conformations on Time of SIV mac251 Acquisition

The monoclonal antibodies (MAbs) NCI05 and NCI09, isolated from a vaccinated macaque that was protected from multiple simian immunodeficiency virus (SIV) challenges, both target an overlapping, conformationally dynamic epitope in SIV envelope variable region 2 (V2). Here, we show that NCI05 recogniz...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of virology 2023-04, Vol.97 (4), p.e0186422
Hauptverfasser:	Stamos, James D, Rahman, Mohammad Arif, Gorini, Giacomo, Silva de Castro, Isabela, Becerra-Flores, Manuel, Van Wazer, David J, N'Guessan, Kombo F, Clark, Natasha M, Bissa, Massimiliano, Gutowska, Anna, Mason, Rosemarie D, Kim, Jiae, Rao, Mangala, Roederer, Mario, Paquin-Proulx, Dominic, Evans, David T, Cicala, Claudia, Arthos, James, Kwong, Peter D, Zhou, Tongqing, Cardozo, Timothy, Franchini, Genoveffa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - isolation & purification Antibodies, Monoclonal - metabolism Antibodies, Viral - blood CHO Cells Cricetulus Epitopes - immunology Macaca - immunology Macaca - virology Models, Molecular Protein Structure, Tertiary Simian Acquired Immunodeficiency Syndrome - immunology Simian Acquired Immunodeficiency Syndrome - prevention & control Simian Immunodeficiency Virus - immunology Viral Proteins - chemistry Viral Proteins - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!