Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

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Veröffentlicht in:	Journal of Virology 2011-06, Vol.85 (12), p.6060-6064
Hauptverfasser:	SIFEI XING, BULLEN, Cynthia K, MARGOLIS, David M, SILICIANO, Janet D, SILICIANO, Robert F, SHROFF, Neeta S, LIANG SHAN, YANG, Hung-Chih, MANUCCI, Jordyn L, BHAT, Shridhar, HAO ZHANG, MARGOLICK, Joseph B, QUINN, Thomas C
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - therapeutic use Biological and medical sciences CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - virology Cells, Cultured Disulfiram - pharmacology Disulfiram - therapeutic use Fundamental and applied biological sciences. Psychology Genes, bcl-2 Genome and Regulation of Viral Gene Expression HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - immunology HIV-1 - physiology Humans Lymphocyte Activation - drug effects Microbiology Miscellaneous Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Transduction, Genetic Virology Virus Activation - drug effects Virus Latency - drug effects
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