Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation
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Veröffentlicht in: | Journal of Virology 2011-06, Vol.85 (12), p.6060-6064 |
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creator | SIFEI XING BULLEN, Cynthia K MARGOLIS, David M SILICIANO, Janet D SILICIANO, Robert F SHROFF, Neeta S LIANG SHAN YANG, Hung-Chih MANUCCI, Jordyn L BHAT, Shridhar HAO ZHANG MARGOLICK, Joseph B QUINN, Thomas C |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/JVI.02033-10</identifier><identifier>PMID: 21471244</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Anti-HIV Agents - therapeutic use ; Biological and medical sciences ; CD4-Positive T-Lymphocytes - drug effects ; CD4-Positive T-Lymphocytes - virology ; Cells, Cultured ; Disulfiram - pharmacology ; Disulfiram - therapeutic use ; Fundamental and applied biological sciences. Psychology ; Genes, bcl-2 ; Genome and Regulation of Viral Gene Expression ; HIV Infections - drug therapy ; HIV Infections - virology ; HIV-1 - drug effects ; HIV-1 - immunology ; HIV-1 - physiology ; Humans ; Lymphocyte Activation - drug effects ; Microbiology ; Miscellaneous ; Proto-Oncogene Proteins c-bcl-2 - genetics ; Proto-Oncogene Proteins c-bcl-2 - metabolism ; Transduction, Genetic ; Virology ; Virus Activation - drug effects ; Virus Latency - drug effects</subject><ispartof>Journal of Virology, 2011-06, Vol.85 (12), p.6060-6064</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011, American Society for Microbiology 2011 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-b8161930a4b2c9595db17073b040e7964656a834904656cc422b28e60766a7b33</citedby><cites>FETCH-LOGICAL-c440t-b8161930a4b2c9595db17073b040e7964656a834904656cc422b28e60766a7b33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126325/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126325/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24242548$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21471244$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SIFEI XING</creatorcontrib><creatorcontrib>BULLEN, Cynthia K</creatorcontrib><creatorcontrib>MARGOLIS, David M</creatorcontrib><creatorcontrib>SILICIANO, Janet D</creatorcontrib><creatorcontrib>SILICIANO, Robert F</creatorcontrib><creatorcontrib>SHROFF, Neeta S</creatorcontrib><creatorcontrib>LIANG SHAN</creatorcontrib><creatorcontrib>YANG, Hung-Chih</creatorcontrib><creatorcontrib>MANUCCI, Jordyn L</creatorcontrib><creatorcontrib>BHAT, Shridhar</creatorcontrib><creatorcontrib>HAO ZHANG</creatorcontrib><creatorcontrib>MARGOLICK, Joseph B</creatorcontrib><creatorcontrib>QUINN, Thomas C</creatorcontrib><title>Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>Anti-HIV Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>CD4-Positive T-Lymphocytes - drug effects</subject><subject>CD4-Positive T-Lymphocytes - virology</subject><subject>Cells, Cultured</subject><subject>Disulfiram - pharmacology</subject><subject>Disulfiram - therapeutic use</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes, bcl-2</subject><subject>Genome and Regulation of Viral Gene Expression</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - virology</subject><subject>HIV-1 - drug effects</subject><subject>HIV-1 - immunology</subject><subject>HIV-1 - physiology</subject><subject>Humans</subject><subject>Lymphocyte Activation - drug effects</subject><subject>Microbiology</subject><subject>Miscellaneous</subject><subject>Proto-Oncogene Proteins c-bcl-2 - genetics</subject><subject>Proto-Oncogene Proteins c-bcl-2 - metabolism</subject><subject>Transduction, Genetic</subject><subject>Virology</subject><subject>Virus Activation - drug effects</subject><subject>Virus Latency - drug effects</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkdFrFDEQxoNY7Fl981mC4FObOkkm2d0Xob1qe-VEkbP4FrLZ3F1Kbrds9q744P_e1G2rEpiEzG--YeYj5A2HY85F-eHyanYMAqRkHJ6RCYeqZEpxfE4mAEIwJcuf--RlStcAHFHjC7IvOBZcIE7I77OQtnEZeruh3711Q9jZwSc6z7Ed6MXsinEaWmrpqYtMsEVv29RsnW_otz5sbP-LTs_wkC7o1MdIv3SNj_Q2DOtuO9BZm8nQruh57GobH6GTsUvo2ldkb2lj8q8f7gPy4_OnxfSCzb-ez6Ync-YQYWB1yTWvJFishatUpZqaF1DIGhB8UWnUSttSYgX3L-dQiFqUXkOhtS1qKQ_Ix1H3ZltvfOPyaL2N5macwHQ2mP8zbVibVbczkgsthcoCR6OA67uUer98quVg7m0w2Qbzx4b8k_G3__Z7gh_3noH3D4BNzsZl3qoL6S-H-SgsM_du5NZhtb4NvTc2bcz1LphSGS6MBg3yDlUxmWw</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>SIFEI XING</creator><creator>BULLEN, Cynthia K</creator><creator>MARGOLIS, David M</creator><creator>SILICIANO, Janet D</creator><creator>SILICIANO, Robert F</creator><creator>SHROFF, Neeta S</creator><creator>LIANG SHAN</creator><creator>YANG, Hung-Chih</creator><creator>MANUCCI, Jordyn L</creator><creator>BHAT, Shridhar</creator><creator>HAO ZHANG</creator><creator>MARGOLICK, Joseph B</creator><creator>QUINN, Thomas C</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20110601</creationdate><title>Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation</title><author>SIFEI XING ; BULLEN, Cynthia K ; MARGOLIS, David M ; SILICIANO, Janet D ; SILICIANO, Robert F ; SHROFF, Neeta S ; LIANG SHAN ; YANG, Hung-Chih ; MANUCCI, Jordyn L ; BHAT, Shridhar ; HAO ZHANG ; MARGOLICK, Joseph B ; QUINN, Thomas C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-b8161930a4b2c9595db17073b040e7964656a834904656cc422b28e60766a7b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Anti-HIV Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>CD4-Positive T-Lymphocytes - drug effects</topic><topic>CD4-Positive T-Lymphocytes - virology</topic><topic>Cells, Cultured</topic><topic>Disulfiram - pharmacology</topic><topic>Disulfiram - therapeutic use</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes, bcl-2</topic><topic>Genome and Regulation of Viral Gene Expression</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - virology</topic><topic>HIV-1 - drug effects</topic><topic>HIV-1 - immunology</topic><topic>HIV-1 - physiology</topic><topic>Humans</topic><topic>Lymphocyte Activation - drug effects</topic><topic>Microbiology</topic><topic>Miscellaneous</topic><topic>Proto-Oncogene Proteins c-bcl-2 - genetics</topic><topic>Proto-Oncogene Proteins c-bcl-2 - metabolism</topic><topic>Transduction, Genetic</topic><topic>Virology</topic><topic>Virus Activation - drug effects</topic><topic>Virus Latency - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SIFEI XING</creatorcontrib><creatorcontrib>BULLEN, Cynthia K</creatorcontrib><creatorcontrib>MARGOLIS, David M</creatorcontrib><creatorcontrib>SILICIANO, Janet D</creatorcontrib><creatorcontrib>SILICIANO, Robert F</creatorcontrib><creatorcontrib>SHROFF, Neeta S</creatorcontrib><creatorcontrib>LIANG SHAN</creatorcontrib><creatorcontrib>YANG, Hung-Chih</creatorcontrib><creatorcontrib>MANUCCI, Jordyn L</creatorcontrib><creatorcontrib>BHAT, Shridhar</creatorcontrib><creatorcontrib>HAO ZHANG</creatorcontrib><creatorcontrib>MARGOLICK, Joseph B</creatorcontrib><creatorcontrib>QUINN, Thomas C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SIFEI XING</au><au>BULLEN, Cynthia K</au><au>MARGOLIS, David M</au><au>SILICIANO, Janet D</au><au>SILICIANO, Robert F</au><au>SHROFF, Neeta S</au><au>LIANG SHAN</au><au>YANG, Hung-Chih</au><au>MANUCCI, Jordyn L</au><au>BHAT, Shridhar</au><au>HAO ZHANG</au><au>MARGOLICK, Joseph B</au><au>QUINN, Thomas C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation</atitle><jtitle>Journal of Virology</jtitle><addtitle>J Virol</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>85</volume><issue>12</issue><spage>6060</spage><epage>6064</epage><pages>6060-6064</pages><issn>0022-538X</issn><eissn>1098-5514</eissn><abstract>Article Usage Stats
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21471244</pmid><doi>10.1128/JVI.02033-10</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Anti-HIV Agents - therapeutic use Biological and medical sciences CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - virology Cells, Cultured Disulfiram - pharmacology Disulfiram - therapeutic use Fundamental and applied biological sciences. Psychology Genes, bcl-2 Genome and Regulation of Viral Gene Expression HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - immunology HIV-1 - physiology Humans Lymphocyte Activation - drug effects Microbiology Miscellaneous Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Transduction, Genetic Virology Virus Activation - drug effects Virus Latency - drug effects |
title | Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation |
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