Mycobacterium tuberculosis embB Codon 306 Mutations Confer Moderately Increased Resistance to Ethambutol In Vitro and In Vivo
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2011-06, Vol.55 (6), p.2891-2896 |
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creator | PLINKE, Claudia WALTER, Kerstin ALY, Sahar EHLERS, Stefan NIEMANN, Stefan |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.00007-10</identifier><identifier>PMID: 21444710</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Animal models ; Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antitubercular Agents ; Antitubercular Agents - pharmacology ; Biological and medical sciences ; Codon ; Dose-Response Relationship, Drug ; Drug Resistance, Bacterial ; Ethambutol ; Ethambutol - pharmacology ; Female ; Hydrolases - genetics ; Mechanisms of Resistance ; Medical sciences ; Mice ; Mice, Inbred C57BL ; Microbial Sensitivity Tests ; Mutation ; Mycobacterium tuberculosis ; Mycobacterium tuberculosis - drug effects ; Mycobacterium tuberculosis - genetics ; Pentosyltransferases ; Pentosyltransferases - genetics ; Pharmacology. Drug treatments</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2891-2896</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011, American Society for Microbiology</rights><rights>Copyright © 2011, American Society for Microbiology 2011 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a505t-f92026e84bd962682a95a1199d2cd85087211fec9dd128adedbd916b6f76344d3</citedby><cites>FETCH-LOGICAL-a505t-f92026e84bd962682a95a1199d2cd85087211fec9dd128adedbd916b6f76344d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101421/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101421/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24242477$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21444710$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PLINKE, Claudia</creatorcontrib><creatorcontrib>WALTER, Kerstin</creatorcontrib><creatorcontrib>ALY, Sahar</creatorcontrib><creatorcontrib>EHLERS, Stefan</creatorcontrib><creatorcontrib>NIEMANN, Stefan</creatorcontrib><title>Mycobacterium tuberculosis embB Codon 306 Mutations Confer Moderately Increased Resistance to Ethambutol In Vitro and In Vivo</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Animal models</subject><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antitubercular Agents</subject><subject>Antitubercular Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Codon</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Resistance, Bacterial</subject><subject>Ethambutol</subject><subject>Ethambutol - pharmacology</subject><subject>Female</subject><subject>Hydrolases - genetics</subject><subject>Mechanisms of Resistance</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Microbial Sensitivity Tests</subject><subject>Mutation</subject><subject>Mycobacterium tuberculosis</subject><subject>Mycobacterium tuberculosis - drug effects</subject><subject>Mycobacterium tuberculosis - genetics</subject><subject>Pentosyltransferases</subject><subject>Pentosyltransferases - genetics</subject><subject>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21444710</pmid><doi>10.1128/AAC.00007-10</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Animal models Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antitubercular Agents Antitubercular Agents - pharmacology Biological and medical sciences Codon Dose-Response Relationship, Drug Drug Resistance, Bacterial Ethambutol Ethambutol - pharmacology Female Hydrolases - genetics Mechanisms of Resistance Medical sciences Mice Mice, Inbred C57BL Microbial Sensitivity Tests Mutation Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Pentosyltransferases Pentosyltransferases - genetics Pharmacology. Drug treatments |
title | Mycobacterium tuberculosis embB Codon 306 Mutations Confer Moderately Increased Resistance to Ethambutol In Vitro and In Vivo |
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