L-Dopa: Selective Toxicity for Melanoma Cells in vitro

In a study of the effect of L-dopa, an intermediate in the biosynthesis of the pigment melanin, on the growth of human and murine melanoma cells a highly selective inhibition of growth was observed for pigmented cell lines (S91A and human melanoma) as compared to the nonpigmented control cells (amel...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1977-07, Vol.197 (4302), p.468-469
Hauptverfasser:	Wick, Michael M., Byers, Lisken, Frei, Emil
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriophages Cell Division - drug effects Cell growth Cell Line Cell lines CHO cells Genomes Inoculation Levodopa - metabolism Levodopa - pharmacology Melanin Melanoma Melanoma - metabolism Melanoma - pathology Mice Pigmentation Vaccination
Online-Zugang:	Volltext
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