Mandelonitrile β-Glucuronide: Synthesis and Characterization

Mandelonitrile β-glucuronide, the compound patented as Laetrile ®, has been synthesized from rabbit liver uridine diphosphate-glucuronosyl transferase immobilized on beaded sepharose, has been analyzed by thin-layer chromatography, nuclear magnetic resonance, and gas chromatography-mass spectrometry...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1977-11, Vol.198 (4317), p.625-627
Hauptverfasser:	Fenselau, Catherine, Pallante, Sharon, Batzinger, Robert P., Benson, Walter R., Barron, Robert P., Sheinin, Eric B., Maienthal, Millard
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Amygdalin - chemical synthesis Amygdalin - pharmacology Glucuronides Isomers Liver Mass spectra Mass Spectrometry Mutation - drug effects Nitriles - chemical synthesis Nitriles - pharmacology Nuclear magnetic resonance Protons Salmonella typhimurium Sulfoxides Urine
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