Δ9-Tetrahydrocannabinol Suppresses Monocyte-Mediated Astrocyte Production of Monocyte Chemoattractant Protein 1 and Interleukin-6 in a Toll-Like Receptor 7–Stimulated Human Coculture

Cannabis is widely used in the United States, with an estimated prevalence of 9.5%. Certain cannabinoids in Cannabis sativa, Δ9-tetrahydrocannabinol (THC) in particular, possess immune-modulating and anti-inflammatory activity. Depending on the context, the anti-inflammatory activity of cannabinoids...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2019-10, Vol.371 (1), p.191-201
Hauptverfasser:	Rizzo, Michael D., Crawford, Robert B., Bach, Anthony, Sermet, Sera, Amalfitano, Andrea, Kaminski, Norbert E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Inflammation, Immunopharmacology, and Asthma
Online-Zugang:	Volltext
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