Axon reflexes evoked by transient receptor potential vanilloid 1 activation are mediated by tetrodotoxin-resistant voltage-gated Na+ channels in intestinal afferent nerves

Capsaicin-sensitive nerves mediate axon vasodilator reflexes in the intestine, but the ion channels underlying action potential (AP) propagation are poorly understood. To examine the role of voltage-gated Na(+) channels underlying these reflexes, we measured vasomotor and electrophysiological respon...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2010-08, Vol.334 (2), p.566-575
Hauptverfasser: Miranda-Morales, M, Ochoa-Cortes, F, Stern, E, Lomax, A E, Vanner, S
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Sprache:eng
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