Endothelin ETB Receptor Is Involved in Sex Differences in the Development of Balloon Injury-Induced Neointimal Formation

The purpose of this study was to evaluate the involvement of endothelin (ET)B receptor-mediated action in the sex differences in balloon injury-induced neointimal formation using the spotting-lethal rat, which carries a naturally occurring deletion in its ETB receptor gene. Male and female ETB-defic...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2011-02, Vol.336 (2), p.533-539
Hauptverfasser:	Kitada, Kento, Yui, Nozomi, Koyama, Maki, Kimura, Kimihiro, Suzuki, Rie, Tanaka, Ryosuke, Mori, Tatsuhiko, Ohkita, Mamoru, Matsumura, Yasuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Catheterization - adverse effects Endothelin-1 - blood Estrogens - pharmacology Female Male Neointima - etiology Ovariectomy Pyridines - pharmacology Rats Rats, Sprague-Dawley Receptor, Endothelin A - genetics Receptor, Endothelin B - genetics Receptor, Endothelin B - physiology RNA, Messenger - analysis Sex Characteristics Systole
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