Inhibition of Inflammatory Cytokine Production from Rheumatoid Synovial Fibroblasts by a Novel IκB Kinase Inhibitor

Nuclear factor-κB (NF-κB) is involved in the pathophysiology of rheumatoid arthritis (RA) and is considered to be a feasible molecular target in treating patients. In the RA joint tissues, activation of NF-κB is often observed together with high amounts of the proinflammatory cytokines tumor necrosi...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2010-04, Vol.333 (1), p.236-243
Hauptverfasser:	Tsuchiya, Atsushi, Imai, Kenichi, Asamitsu, Kaori, Waguri-Nagaya, Yuko, Otsuka, Takanobu, Okamoto, Takashi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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