Enhanced Gastrointestinal Motility with Orally Active Ghrelin Receptor Agonists

The orexigenic peptide ghrelin has been shown to have prokinetic activity in the gastrointestinal (GI) system of several species, including humans. In this series of experiments, we have evaluated the prokinetic activity of novel, small-molecule ghrelin receptor (GhrR) agonists after parenteral and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2009-06, Vol.329 (3), p.1178-1186
Hauptverfasser:	Charoenthongtrakul, Soratree, Giuliana, Derek, Longo, Kenneth A., Govek, Elizabeth K., Nolan, Anna, Gagne, Samantha, Morgan, Kristen, Hixon, Jeffrey, Flynn, Neil, Murphy, Brian J., Hernández, Andres S., Li, Jun, Tino, Joseph A., Gordon, David A., DiStefano, Peter S., Geddes, Brad J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Body Weight - drug effects Bowen's Disease - chemically induced Bowen's Disease - drug therapy Bowen's Disease - physiopathology Central Nervous System - drug effects Defecation - drug effects Eating - drug effects Gastric Emptying - drug effects Gastrointestinal Motility - drug effects Gastrointestinal Transit - drug effects Ghrelin - administration & dosage Ghrelin - pharmacology Intestine, Small - drug effects Intestine, Small - physiology Male Mice Mice, Inbred C57BL Mice, Knockout Morphine - pharmacology Peptide Hormones - administration & dosage Peptide Hormones - blood Peptide Hormones - pharmacology Rats Rats, Sprague-Dawley Receptors, Ghrelin - agonists Receptors, Ghrelin - genetics Receptors, Ghrelin - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!